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Hi Tina, You might consider checking out our other article, specifically about the localized reactions people are getting on their arms

Cancer Sci 107(5): 583-589

Chen, Y., Jiang, Y., Yang, Y., Huang, X

For progressive forms, such as secondary progressive MS (SPMS) and primary progressive MS (PPMS), therapeutic options are limited compared to relapsingremitting MS (RRMS) [141]